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Two-carbon nitrogen ring bases (adenine and guanine) covalently linked to a sugar (ribose or deoxyribose) and one to three phosphate groups; can function as extracellular messengers, antimetabolites, and chain terminators that inhibit viral DNA polymerase.
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Adenosine monophosphate (AMP) is an adenosine A1 receptor agonist and a key cellular metabolite involved in regulating energy homeostasis and signal transduction. It demonstrates significant antiviral activity against HSV-1 and HSV-2.
Acts as an adenosine A1 receptor agonist
Demonstrates significant antiviral activity against HSV-1 and HSV-2
Functions as a key cellular metabolite regulating energy homeostasis and signal transduction
Shows negligible cell toxicity at 25 to 400 μM in RAW264.7 cells
Significantly attenuates mRNA expression of TNF-α and IL-6 in RAW264.7 cells
Reduces recruitment of NF-κB p65 to TNF-α, IL-6, and IL-1β gene promoters
Increases hepatic adenosine levels in C57BL/6J mice
Improves survival rate and lowers serum AST and ALT levels in treated mice
Attenuates necrosis and reduces infiltration of inflammatory cells in vivo
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Inosine 5′-diphosphate sodium is a purine ribonucleoside 5′-diphosphate with inosine as the nucleobase. It participates in intracellular energy metabolism and signal transduction processes.
Purine ribonucleoside 5′-diphosphate with inosine as the nucleobase
Participates in intracellular energy metabolism
Participates in signal transduction processes
Functions as an endogenous metabolite
Classified as a nucleotide analog
Used in research for respiratory disease
Used in research for metabolic or endocrine disease
Used in research for pulmonary disease
Used in research for lung fibrosis
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Alpha-Guanosine is a purine nucleoside analog that exhibits broad antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis.
Purine nucleoside analog
Exhibits broad antitumor activity
Targets indolent lymphoid malignancies
Inhibits DNA synthesis
Induces apoptosis
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Adenosine 5'-phosphosulfate disodium is a metabolism intermediate of sulfur. It can be used to study sulfotransferases and sulforeductases in various organisms.
For research use only.
Not sold to patients.
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ATP-Red 1 is a multisite-binding switchable fluorescent probe designed for the selective and rapid detection of intracellular ATP concentrations in living cells. It features excitation at 510 nm and emission at 590 nm, making it suitable for various cell-staining applications.
Selectively responds to intracellular ATP
Rapid detection in living cells
Excitation at 510 nm
Emission at 590 nm
Suitable for fluorescence microscopy or flow cytometry
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L-Adenosine is the L-enantiomer of adenosine used as a research reagent and probe. It exhibits weak adenosine deaminase (ADA) inhibitory activity and is supplied in high purity for biochemical and pharmacological studies.
L-enantiomer of adenosine with defined stereochemistry.
Weak adenosine deaminase (ADA) inhibitor suitable for enzyme assays.
High reported purity (99.8%).
Molecular formula C10H13N5O4 and molecular weight 267.25 g/mol.
Available as solid and as pre-made 10 mM DMSO stock for convenient use.
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Adenosine 5'-monophosphate disodium is an orally active purine nucleotide that participates in ATP metabolism. It is also a ligand for the adenosine 2B receptor. This compound can activate AMPK in skeletal muscle, ameliorating insulin resistance and impaired glucose metabolism. It can be used for research on diabetes.
Orally active purine nucleotide
Participates in ATP metabolism
Ligand for the adenosine 2B receptor
Activates AMPK in skeletal muscle
Ameliorates insulin resistance
Improves impaired glucose metabolism
Can be used for research on diabetes
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L-Adenosine is an enantiomeric nucleoside used as a biochemical probe for adenosine uptake and metabolism. It displays weak adenosine deaminase (ADA) inhibitory activity and is supplied in high-purity forms for laboratory research.
High purity (≈99.8%).
Molecular weight 267.25 g/mol.
CAS number 3080-29-3.
Available as solid and 10 mM DMSO solution formats.
Suitable for biochemical, uptake, and metabolism studies.
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Adenosine 5'-triphosphate-15N5 ammonium is the 15N labeled Adenosine 5'-triphosphate ammonium. This compound offers versatility in research applications.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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