Purine nucleotides
Medchemexpress LLC Acyclovir triphosphate sodium | 221119-43-3 | 99.7% | C8H14N5O12P3.xNa | 25 MG
Acyclovir triphosphate sodium (AcycloGTP sodium) is a derivative of Acyclovir that functions as an inhibitor of viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). This compound is also recognized as an inhibitor of HIV-1 reverse transcriptase, ultimately leading to the termination of viral DNA synthesis. It is intended for research use only.
- Competitively inhibits viral DNA polymerase.
- Acts as an analog to deoxyguanosine triphosphate (dGTP).
- Inhibits HIV-1 reverse transcriptase.
- Causes termination of viral DNA synthesis.
- Available for research purposes.
![Medchemexpress LLC 1-[3-(difluoromethyl)-1,2-thiazol-5-yl]-3-[2-fluoro-5-(hydroxymethyl)-4-pyridinyl]urea | 2270879-17-7 | 99.7% | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000234159.png-250.jpg)
Medchemexpress LLC 1-[3-(difluoromethyl)-1,2-thiazol-5-yl]-3-[2-fluoro-5-(hydroxymethyl)-4-pyridinyl]urea | 2270879-17-7 | 99.7% | 1 ML
BRM/BRG1 ATP Inhibitor-1 is an orally active, allosteric small-molecule inhibitor of the chromatin-remodeling ATPases BRM (SMARCA2) and BRG1 (SMARCA4), supplied for research use. It is offered as a white to off-white solid and as a 10 mM solution in DMSO (1 mL), and it shows low-nanomolar potency in biochemical assays (IC50 <5 nM).
- Allosteric dual inhibitor of BRM and BRG1.
- Molecular formula C11H9F3N4O2S, molecular weight ≈318.3 g/mol.
- High reported purity for research applications.
- Available as a solid and as a 10 mM DMSO solution (1 mL).
- Recommended solvent: DMSO; prepare stock solutions and store at -80°C or -20°C per stability guidance.
Medchemexpress LLC Adenosine receptor antagonist 3 | 2400864-80-2 | 99.1% | C16H14N6S | 100 MG
Adenosine receptor antagonist 3 is a potent antagonist of adenosine receptor. It has potential for the research of cancer disease, as extracted from patent WO2019233994A1, compound 1. It is for research use only.
- Potent antagonist of adenosine receptor
- Potential for cancer disease research
- For research use only
Cambridge Isotope Laboratories DL-2-Hydroxyglutaric acid disodium salt (unlabeled) 0 01 g
DL-2-Hydroxyglutaric acid disodium salt (unlabeled) 0 01 g
Apexbio Technology LLC Adenosine 5'-monophosphate disodium 4578-31-8 500mg
Adenosine 5p-monophosphate disodium is a purine nucleotide derivative composed of adenosine linked to a phosphate group presented as the disodium salt It functions as an intermediate in cellular metabolism contributing directly to ATP biosynthesis and degradation pathways and serves as a biochemical precursor and degradation product in energy exchange reactions Adenosine 5p-monophosphate disodium exerts its biological activity as part of pathways regulating gene expression protein synthesis modulation and intracellular signal transduction In biomedical research it is utilized to investigate mechanisms underlying energy metabolism nucleic acid metabolism and cellular homeostasis Based on these characteristics Adenosine 5p-monophosphate disodium holds research potential in studies of metabolic function ATP-dependent signaling pathways and related disease models
Cambridge Isotope Laboratories DL-2-Hydroxyglutaric acid disodium salt (unlabeled) 0 1 g
DL-2-Hydroxyglutaric acid disodium salt (unlabeled) 0 1 g
Apexbio Technology LLC Adenosine 58-61-7 10mM (in 1mL DMSO)
Adenosine (CAS 58-61-7) is a purine nucleoside consisting of adenine covalently linked to a ribose sugar via a -N9-glycosidic bond Endogenously adenosine modulates cellular signaling through activation of specific G protein-coupled adenosine receptors (A1 A2A A2B and A3) influencing diverse physiological processes such as neurotransmission vasodilation and immune responses In biomedical research adenosine is widely utilized to investigate purinergic signaling pathways cardiac function and the regulation of inflammatory and neuroprotective mechanisms as well as serving as a pharmacological tool in receptor binding and functional assays
Medchemexpress LLC Alpha guanosine | 15398-66-0 | 96.0% | 283.24 g/mol | C10H13N5O5 | 10 MG
Alpha guanosine is a purine nucleoside analog used in biochemical and pharmacological research to study nucleoside metabolism and antimetabolite activity. The product is supplied as a purified powder with documented physicochemical properties, recommended storage conditions, and solubility information to support preparation of stable stock solutions for laboratory use.
- Purity: 95.96%
- Molecular formula: C10H13N5O5
- Molecular weight: 283.24 g/mol
- Soluble in DMSO at 12.5 mg/mL with ultrasonic warming to 60°C
- Powder recommended storage: -20°C, stable for up to 3 years
- In-solution stability: -80°C for 6 months, -20°C for 1 month
- Available in small milligram pack sizes for research applications
Apexbio Technology LLC ATP disodium salt 987-65-5 10mM (in 1mL H2O)
ATP disodium salt (CAS 987-65-5) is a nucleotide derivative serving as the primary energy carrier in cellular metabolism It provides chemical energy through phosphate group transfer reactions facilitating numerous biochemical processes In addition to its metabolic functions ATP acts as a coenzyme involved in intracellular signaling and protein phosphorylation pathways Due to these biochemical roles ATP disodium salt is widely utilized in research exploring cellular metabolism signaling mechanisms and energy regulation pathways Recently ATP s function as a signaling molecule in immune responses and inflammation modulation has also gained attention
Apexbio Technology LLC 8-Aza-ATP 50ul (100 mM)
8-Aza-ATP is a structural analog of ATP characterized by the substitution of the carbon atom at the 8-position of the purine ring with nitrogen resulting in an 8-azapurine nucleotide moiety Due to this structural alteration 8-Aza-ATP competitively interacts with ATP-binding sites on enzymes thereby modulating their catalytic activities This compound serves as a tool in biochemical research to elucidate enzyme-substrate recognition nucleotide binding specificity and catalytic mechanisms of ATP-dependent enzymes Additionally it is utilized in the study of cellular energy metabolism signal transduction pathways and nucleotide-mediated regulatory processes contributing to understanding relevant physiological and pathological mechanisms
Medchemexpress LLC Guanosine triphosphate trisodium salt | 36051-31-7 | 589.13 | 1 ML
Guanosine triphosphate trisodium salt, 100 mM Solution, PCR Grade is a solution prepared from guanosine triphosphate at a concentration of 100 mM. It is free of DNase, RNase, and phosphatase contamination, making it suitable for various molecular biology research applications.
- Prepared from guanosine triphosphate at 100 mM concentration.
- Free of DNase contamination.
- Free of RNase contamination.
- Free of phosphatase contamination.
- Suitable for molecular biology research.
Medchemexpress LLC GTP-14564 | 34823-86-4 | 99.9% | 234.25 | 25 MG
GTP-14564 is a tyrosine kinase inhibitor that targets internal tandem duplication (ITD) and FLT3. It inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
- Tyrosine kinase inhibitor
- Targets ITD and FLT3
- Inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells
Medchemexpress LLC Adenosine | 58-61-7 | 100.0% | 50 G
Adenosine is a ubiquitous and BBB-permeable endogenous autacoid, acting through four G protein-coupled receptors (A1, A2A, A2B, and A3). It influences nearly all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation. As an extracellular signaling molecule derived from 5'-adenosine triphosphate (ATP) and 5'-adenosine monophosphate (AMP), it plays a critical role in cellular processes.
- Influences neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
- Acts via G protein-coupled receptors: A1, A2A, A2B, and A3.
- Inhibits cell viability and triggers ER stress in HepG2 cells at high concentrations.
- Induces apoptosis and autophagy in HepG2 cells via the AMPK/mTOR pathway.